Opportunity Information: Apply for RFA NR 23 002
The Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities funding opportunity (RFA-NR-23-002) is a National Institutes of Health (NIH) discretionary grant mechanism using the R01 activity, with clinical trials listed as optional. It is designed to respond to a pressing public health problem: persistent and unacceptable disparities in maternal health outcomes, particularly affecting racial and ethnic minority women. The initiative is centered on generating practical, evidence-based insights by supporting research that either develops new supportive care models or rigorously evaluates existing models and real-world policy or program efforts that aim to reduce inequities and prevent adverse maternal outcomes.
A defining feature of this opportunity is its focus on integrated models of care, meaning approaches that do more than address clinical care in isolation. Proposed models are expected to connect improvements in healthcare access and/or healthcare quality with deliberate strategies that confront structural and social inequities that shape pregnancy risks and outcomes. In practice, this can include healthcare delivery interventions (for example, team-based care, care coordination, patient navigation, community health worker or doula integration, telehealth-enabled prenatal/postpartum monitoring, or improved screening and referral pathways) that are intentionally designed to work alongside efforts that reduce barriers tied to social conditions, systemic bias, resource inequities, and other upstream drivers of risk. The goal is to move beyond describing disparities and instead test or evaluate interventions and systems-level strategies that can measurably improve outcomes.
The scope of supported research explicitly includes both original intervention studies and evaluations of the impact of policies and programs. That policy/program evaluation component is broad and can include federal, tribal, state, local, or organizational initiatives, recognizing that maternal outcomes are shaped not only by clinical encounters but also by how services are organized, funded, regulated, and accessed. Projects can examine whether and how specific policies or programs change maternal health outcomes, for whom they work best, and under what implementation conditions they are most effective, including impacts on equity.
The outcomes of interest cover a wide range of maternal health issues. The announcement highlights pregnancy-related morbidity such as hypertension, diabetes, obesity, cerebrovascular disease, and mental illness, and it also includes severe maternal morbidity. It extends to pregnancy-associated factors that can contribute to adverse outcomes, including violence exposure (explicitly including firearm violence), substance use disorders, and dietary patterns. Maternal mortality is also an outcome of interest, reflecting the seriousness of the disparities this initiative aims to address. Overall, the opportunity supports research that links integrated care and equity-focused strategies to tangible improvements in maternal health and survival.
Eligibility is broad and includes many types of U.S.-based applicants: state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other eligible entities. The announcement also emphasizes inclusion of organizations that often play key roles in addressing inequities, listing additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, Indian/Native American tribal governments that are not federally recognized, and U.S. territories or possessions.
At the same time, the opportunity draws clear boundaries around non-U.S. participation. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as applicants. Non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, which generally means a U.S. applicant may include certain well-justified international elements within the project if they meet NIH policy requirements, even though a foreign institution cannot serve as the primary applicant.
The funding opportunity was created on February 27, 2023, and listed an original closing date of May 1, 2023. It is associated with CFDA numbers 93.307, 93.313, and 93.361. The public summary does not specify an award ceiling or expected number of awards, so applicants typically would need to consult the full funding announcement and NIH guidance for budget expectations, project period norms, and review considerations. Overall, this R01 opportunity is aimed at advancing actionable, equity-centered research on integrated care and policy/program impacts to reduce maternal morbidity and mortality among women experiencing persistent disparities.Apply for RFA NR 23 002
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307, 93.313, 93.361.
- This funding opportunity was created on 2023-02-27.
- Applicants must submit their applications by 2023-05-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the AIM of Care funding opportunity?
The Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities opportunity (RFA-NR-23-002) is an NIH discretionary research grant opportunity focused on reducing persistent and unacceptable disparities in maternal health outcomes, particularly those affecting racial and ethnic minority women.
What grant mechanism does this opportunity use?
This opportunity uses the NIH R01 activity code.
Are clinical trials allowed under this opportunity?
Yes. Clinical trials are listed as optional.
What is the main public health problem this funding is trying to address?
The opportunity is intended to address persistent disparities in maternal health outcomes, including serious adverse outcomes and mortality, with particular attention to inequities affecting racial and ethnic minority women.
What kinds of research projects does this opportunity support?
It supports research that develops new supportive models of care and research that rigorously evaluates existing models, including real-world policy and program efforts intended to reduce inequities and prevent adverse maternal outcomes.
What does "integrated models of care" mean in this announcement?
In this opportunity, integrated models of care are approaches that go beyond clinical care alone. Proposed models are expected to link healthcare access and/or healthcare quality improvements with deliberate strategies that confront structural and social inequities that shape pregnancy risks and outcomes.
What are examples of healthcare delivery interventions that fit the scope?
Examples mentioned include team-based care, care coordination, patient navigation, integrating community health workers or doulas, telehealth-enabled prenatal/postpartum monitoring, and improved screening and referral pathways, when these are intentionally designed alongside equity-focused strategies.
Does the opportunity fund projects focused on social and structural drivers of inequity?
Yes. The opportunity emphasizes confronting barriers tied to social conditions, systemic bias, resource inequities, and other upstream drivers of pregnancy risk and outcomes, as part of integrated care approaches.
Is this opportunity only for creating new interventions, or can it evaluate existing efforts?
It includes both. Projects may develop original interventions or evaluate existing models, as well as assess the impact of real-world policies and programs.
What types of policies and programs can be evaluated?
The policy/program evaluation component can include federal, tribal, state, local, or organizational initiatives, reflecting that maternal outcomes are influenced by how services are organized, funded, regulated, and accessed.
What kinds of questions can policy or program evaluations address?
Projects can examine whether and how policies or programs change maternal health outcomes, for whom they work best, and under what implementation conditions they are most effective, including impacts on equity.
What maternal health outcomes are of interest?
The announcement highlights pregnancy-related morbidity (including hypertension, diabetes, obesity, cerebrovascular disease, and mental illness), severe maternal morbidity, maternal mortality, and pregnancy-associated factors that can contribute to adverse outcomes.
What pregnancy-associated factors are specifically mentioned?
Examples include exposure to violence (explicitly including firearm violence), substance use disorders, and dietary patterns.
Is the focus limited to pregnancy, or does it include postpartum outcomes too?
Postpartum is explicitly referenced through examples such as telehealth-enabled prenatal/postpartum monitoring, and the overall focus is on improving pregnancy outcomes and reducing maternal morbidity and mortality.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based applicants, such as state/county/city governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other eligible entities.
Are community-based or faith-based organizations eligible?
Yes. The announcement emphasizes inclusion of organizations that often play key roles in addressing inequities and explicitly lists faith-based or community-based organizations as eligible applicants.
Are minority-serving institutions eligible to apply?
Yes. The announcement lists several, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and others.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed among eligible applicants.
Can federal agencies apply?
Yes. Eligible federal agencies are included in the list of eligible applicants.
Are non-U.S. (foreign) institutions eligible to apply as the applicant organization?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as applicants.
Can a non-U.S. component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are not eligible to apply.
Are foreign components allowed at all?
Yes. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. This generally means a U.S. applicant may include well-justified international elements within the project if they meet NIH policy requirements, even though a foreign institution cannot serve as the primary applicant.
When was this funding opportunity created, and what was the listed closing date?
The opportunity was created on February 27, 2023, and it listed an original closing date of May 1, 2023.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with CFDA numbers 93.307, 93.313, and 93.361.
Does the public summary state the maximum award amount or the expected number of awards?
No. The public summary does not specify an award ceiling or the expected number of awards.
Where would an applicant typically look for budget expectations and other details not included in the summary?
Based on the summary, applicants would typically need to consult the full funding announcement and NIH guidance for budget expectations, project period norms, and review considerations.
What is the overall intent of this R01 opportunity?
Overall, it aims to advance actionable, equity-centered research on integrated care and on policy/program impacts to reduce maternal morbidity and mortality among women experiencing persistent disparities.
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