Opportunity Information: Apply for RFA CK 22 006

The grant opportunity titled "Clinical and Applied Research Strategies for the Prevention and Control of Fungal Diseases" (Funding Opportunity Number RFA CK 22 006) is a discretionary funding program from the U.S. Department of Health and Human Services, administered by the Centers for Disease Control and Prevention (CDC) through its ERA system. It is designed to fund practical, real-world clinical and applied research aimed at reducing illness and death linked to fungal diseases globally, including infections caused by both well-known fungi and newly emerging fungal pathogens. The central public health goal behind the program is to generate evidence, tools, and strategies that can improve prevention and control efforts and ultimately lower the burden of fungal disease in diverse settings.

This opportunity uses a cooperative agreement as its funding instrument, which typically means the CDC expects to have substantial involvement in the funded work compared with a standard grant. In practical terms, applicants should anticipate an active partnership model where the CDC may collaborate on technical direction, coordination, and public health relevance to ensure the research outputs can be translated into meaningful prevention and control impacts. The activity category is health, and the program is associated with CFDA number 93.084, indicating it falls within CDC public health assistance programming.

Funding is capped at an award ceiling of $500,000 per award, with an expected total of three awards. This suggests a competitive program focused on a small number of projects that are likely to be high-impact, feasible, and strongly aligned with CDC priorities in fungal disease prevention and control. Because the emphasis is on clinical and applied research, the strongest projects would typically be those that can move beyond basic science and produce actionable findings, such as improved diagnostic approaches in clinical or public health settings, better strategies for identifying and responding to outbreaks, optimized prevention measures in high-risk populations, or interventions that reduce morbidity and mortality. The global scope noted in the description indicates projects may address fungal threats internationally, not solely within the United States, as long as the work supports the overarching aim of reducing worldwide fungal disease burden.

Eligibility is broad and includes multiple types of government entities and public-serving organizations. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations that are not federally recognized tribal governments; and nonprofit organizations, including both 501(c)(3) nonprofits and non-501(c)(3) nonprofits (in both cases, other than institutions of higher education). The listing also includes an "Others" category with direction to consult the additional eligibility text in the full announcement for clarification, meaning some additional applicant types may qualify depending on the CDCs specific criteria and program rules.

Key timing details show the opportunity was created on December 15, 2021, with an original application closing date of February 15, 2022. Applications were required to be submitted electronically, and the deadline was 5:00 pm Eastern Time on the due date. Overall, the program is positioned as a targeted CDC investment in applied research that can strengthen real-world prevention and control of fungal diseases, with the expectation that funded projects will contribute to reducing severe outcomes and deaths from fungal infections driven by both established and emerging threats.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Clinical and Applied Research Strategies for the Prevention and Control of Fungal Diseases" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
  • This funding opportunity was created on Dec 15, 2021.
  • Applicants must submit their applications by Feb 15, 2022 Electronically submitted applications must be submitted no later than 500 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA CK 22 006

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