Opportunity Information: Apply for RFA DK 17 001
The Silvio O. Conte Digestive Diseases Research Core Centers (P30) funding opportunity (RFA-DK-17-001) is a National Institutes of Health grant program administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to support Digestive Diseases Research Core Centers (DDRCCs). These centers are intended to strengthen and accelerate digestive and liver disease research by creating an organized, collaborative environment where basic science and clinical investigators work in closer coordination. Rather than primarily funding many separate research projects, the P30 mechanism focuses on building shared infrastructure and services (the "cores") that investigators can use to improve the quality, efficiency, and impact of their ongoing, independently supported research.
A key idea behind the program is the core center model: the grant supports shared resources, facilities, and expertise that multiple investigators use in common, which helps reduce duplication and makes advanced capabilities more cost-effective. In practical terms, a DDRCC typically provides centralized services such as specialized lab platforms, data management or biostatistics support, clinical research resources, tissue or biospecimen capabilities, imaging or pathology support, and other shared technical or administrative functions that remove barriers for participating researchers. The goal is to boost productivity, create synergy among research groups, and spark new collaborative projects and ideas that might not emerge if investigators were working in isolation.
Each proposed center must be organized around a clear central theme that reflects the strengths and focus of the participating investigators in digestive and/or liver diseases. Importantly, that theme must align with NIDDKs primary mission areas and should not fall mainly within topics for which another NIH Institute or Center is typically the primary funder. In other words, applicants need to show that the scientific focus squarely fits within NIDDK-supported digestive and liver disease priorities and that the center will meaningfully enhance the effectiveness of existing research programs by providing shared resources and fostering communication across disciplines.
Eligibility is broad across U.S.-based institutions and organizations. Eligible applicants listed for this opportunity include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education, when specified); for-profit organizations (other than small businesses) as well as small businesses; and other categories. The announcement also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, the FOA makes clear that non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed, which effectively confines supported activities to domestic settings.
From an administrative standpoint, the opportunity is categorized as discretionary funding, uses the grant funding instrument, and falls under the health and food/nutrition activity category (CFDA 93.847). The source data notes an award ceiling of $750,000. The original closing date shown is 2017-12-05, and the FOA creation date is 2016-12-01, indicating this specific announcement is associated with that application cycle. Overall, the program is designed for institutions that already have a substantial base of digestive and/or liver disease research and want to knit that work together through shared cores, coordinated leadership, and an organizing scientific theme that improves collaboration and amplifies the impact of NIDDK-relevant research.Apply for RFA DK 17 001
- The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Silvio O. Conte Digestive Diseases Research Core Centers (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on 2016-12-01.
- Applicants must submit their applications by 2017-12-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the Silvio O. Conte Digestive Diseases Research Core Centers (P30) opportunity?
It is an NIH grant funding opportunity administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to support Digestive Diseases Research Core Centers (DDRCCs). The opportunity is identified as RFA-DK-17-001 and uses the P30 center core grant mechanism.
What is the main purpose of a Digestive Diseases Research Core Center (DDRCC)?
The purpose is to strengthen and accelerate digestive and liver disease research by building an organized, collaborative environment where basic science and clinical investigators coordinate more closely, supported by shared core resources and services.
What does the P30 mechanism primarily fund in this program?
Rather than primarily funding many separate research projects, the P30 mechanism focuses on shared infrastructure and services (the "cores") that investigators can use to improve the quality, efficiency, and impact of their ongoing, independently supported research.
What is meant by the "core center model" in this funding opportunity?
The core center model supports shared resources, facilities, and expertise that multiple investigators use in common. This is intended to reduce duplication and make advanced capabilities more cost-effective across participating research groups.
What kinds of shared services might a DDRCC provide?
Based on the opportunity description, DDRCCs typically provide centralized services such as specialized laboratory platforms, data management or biostatistics support, clinical research resources, tissue or biospecimen capabilities, imaging or pathology support, and other shared technical or administrative functions.
How does a DDRCC help participating investigators?
By providing shared cores and centralized expertise, a DDRCC aims to remove barriers for researchers, boost productivity, increase synergy among research groups, and encourage new collaborations and ideas that may be less likely to develop if investigators work in isolation.
Does the center need a specific scientific focus or theme?
Yes. Each proposed center must be organized around a clear central theme that reflects the strengths and focus of participating investigators in digestive and/or liver diseases.
How must the center theme relate to NIDDK priorities?
The theme must align with NIDDK's primary mission areas and should not fall mainly within topics for which another NIH Institute or Center is typically the primary funder. Applicants are expected to show the focus fits within NIDDK-supported digestive and liver disease priorities.
Is this program intended for institutions with existing research activity?
Yes. The description indicates the program is designed for institutions that already have a substantial base of digestive and/or liver disease research and want to connect that work through shared cores, coordinated leadership, and an organizing scientific theme.
Who administers this funding opportunity?
The program is administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).
What types of applicants are eligible to apply?
Eligibility is broad across U.S.-based institutions and organizations. Eligible applicants listed include various levels of government (state, county, city or township, special district), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, other Native American tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations (with or without 501(c)(3) status, as specified), for-profit organizations (other than small businesses) as well as small businesses, and other categories identified in the announcement.
Are minority-serving and community-based organizations included as eligible applicants?
Yes. The announcement explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
Are non-U.S. entities allowed to apply?
No. The opportunity states that non-U.S. entities are not eligible to apply.
Can a U.S. organization include non-U.S. components or foreign components in the project?
No. The announcement states that non-U.S. components of U.S. organizations are not eligible and that foreign components (as defined by NIH policy) are not allowed, effectively confining supported activities to domestic settings.
What type of funding is this categorized as?
It is categorized as discretionary funding.
What is the funding instrument for this opportunity?
The opportunity uses a grant funding instrument.
What activity category and CFDA number are associated with this opportunity?
The source information places it under the health and food/nutrition activity category and lists CFDA 93.847.
What is the award ceiling listed for this opportunity?
The source data notes an award ceiling of $750,000.
What are the key dates provided for this announcement?
The FOA creation date is listed as 2016-12-01, and the original closing date shown is 2017-12-05, indicating this specific announcement is associated with that application cycle.
Does this opportunity mainly fund new individual research projects?
No. The description emphasizes that the P30 mechanism is focused on building shared cores and infrastructure to support and enhance ongoing, independently supported research, rather than primarily funding many separate research projects.
What overall outcomes is the program trying to achieve?
The program aims to improve research quality and efficiency, increase impact, reduce duplication of resources, strengthen collaboration between basic and clinical investigators, and amplify NIDDK-relevant digestive and liver disease research through shared infrastructure and coordinated center activities.
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| Funding Opportunity |
|---|
| Therapeutic Targeting Of The Human Islet Environment (UC4) Apply for RFA DK 17 003 Funding Number: RFA DK 17 003 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| Competitive Collaborative Projects for Human Islet Biology (UC4) Apply for RFA DK 17 004 Funding Number: RFA DK 17 004 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $350,000 |
| Limited Competition: Follow-up on Subjects and Immunological Assessments in The Environmental Determinants of Diabetes In The Young Study (TEDDY) (UC4) Apply for RFA DK 16 504 Funding Number: RFA DK 16 504 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) Apply for PAR 17 123 Funding Number: PAR 17 123 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42) Apply for PA 17 131 Funding Number: PA 17 131 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44) Apply for PA 17 130 Funding Number: PA 17 130 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care (R18) Apply for PAR 17 177 Funding Number: PAR 17 177 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Evaluating Natural Experiments in Healthcare to Improve Diabetes Prevention and Treatment (R18) Apply for PAR 17 178 Funding Number: PAR 17 178 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Planning Grants for Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care (R34) Apply for PAR 17 180 Funding Number: PAR 17 180 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $150,000 |
| Pragmatic Research in Healthcare Settings to improve Kidney Disease Prevention and Care (R18) Apply for RFA DK 17 008 Funding Number: RFA DK 17 008 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $325,000 |
| Limited Competition: Data Coordinating Center for Type 1 Diabetes TrialNet (UC4) Apply for RFA DK 17 507 Funding Number: RFA DK 17 507 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R43/R44) Apply for RFA HL 17 023 Funding Number: RFA HL 17 023 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R41/R42) Apply for RFA HL 17 024 Funding Number: RFA HL 17 024 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (UC4) Apply for RFA HL 17 027 Funding Number: RFA HL 17 027 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| NIDDK Central Repositories Non-renewable Sample Access (X01) Apply for PAR 17 270 Funding Number: PAR 17 270 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Therapeutic Strategies for the Converging TB/T2DM/HIV Epidemics (R01) Apply for PA 17 283 Funding Number: PA 17 283 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Administrative Supplements for Participation in the Concept to Clinic: Commercializing Innovation (C3i) Program (Admin Supp) Apply for PA 17 286 Funding Number: PA 17 286 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Psychological, Behavioral, and Neurocognitive-Focused Ancillary Studies to the Molecular Transducers of Physical Activity in Humans Consortium (MoTrPAC) (U01) Apply for RFA DK 17 009 Funding Number: RFA DK 17 009 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $3,000,000 |
| Center for Identification and Study of Individuals with Atypical Diabetes Mellitus (U54) Apply for RFA DK 17 006 Funding Number: RFA DK 17 006 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort Scientific and Data Coordinating Center (U24) Apply for RFA DK 17 506 Funding Number: RFA DK 17 506 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $2,250,000 |
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