Opportunity Information: Apply for HT942525PRCRPIPA
The FY25 DOD Peer Reviewed Cancer Research Program (PRCRP) Impact Award is a discretionary grant opportunity administered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed to fund mature cancer research projects that are ready to meaningfully influence clinical cancer care in the near term. The work must align with one of the congressionally directed FY25 PRCRP topic areas, and applicants are expected to clearly explain how the proposed project will advance cancer research knowledge and translate into improvements in patient care and/or treatment options within the Military Health System (MHS).
This mechanism is aimed at studies that are beyond early discovery and are supported by preliminary data. Including feasibility-supporting preliminary data is not optional; it is a core requirement to demonstrate the project is sufficiently developed and likely to succeed. Reviewers will be looking for a strong, credible line from the proposed research to real-world clinical impact in cancer, rather than long-range or purely exploratory outcomes. A notable feature of the Impact Award is that it allows clinical trials, which signals that the program is open to late-stage translational work and clinically oriented study designs when they are justified and well supported.
The program allows either a single-PI application or a partnered, two-PI structure. In the partnered model, the two investigators are designated as the Initiating PI and the Partnering PI. The Initiating PI is responsible for submitting the pre-application, but at the full application stage both investigators must submit their own application materials. The Partnering PI submits an abbreviated application package that focuses on their specific portion of the overall research plan. An important administrative dependency applies: if either the initiating or partnering application is rejected or administratively withdrawn, both applications tied to that joint project may be withdrawn, meaning the two-PI approach requires close coordination and parallel compliance by both investigators.
For FY25, a key change is that funding limits are expressed as total cost limits, meaning the cap includes both direct costs and indirect costs combined. The opportunity is listed under CFDA 12.420 (science and technology and other research and development). Eligibility is described as unrestricted. The funding opportunity number is HT942525PRCRPIPA. The original closing date is September 25, 2025. The listing anticipates about 30 awards, and while an award ceiling value is referenced in the source listing, it is not provided in the excerpted text.Apply for HT942525PRCRPIPA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Peer Reviewed Cancer, Impact Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2025-05-22.
- Applicants must submit their applications by 2025-09-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 30 candidate(s).
- Eligible applicants include: Unrestricted.
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|---|
| Staff Research Program Apply for W911NF25S0007 Funding Number: W911NF25S0007 Agency: Dept of the Army -- Materiel Command Category: Science and Technology and other Research and Development Funding Amount: $10,000,000 |
| DoD Toxic Exposures Investigator-Initiated Research Award Apply for HT942525TERPIIRA Funding Number: HT942525TERPIIRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Toxic Exposures Translational Research Partnership Award Apply for HT942525TERPTRPA Funding Number: HT942525TERPTRPA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Toxic Exposures Clinical Trial Partnership Award Apply for HT942525TERPCTPA Funding Number: HT942525TERPCTPA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Breast Cancer, Breakthrough Award Levels 1 and 2 Apply for HT942525BCRPBTA122 Funding Number: HT942525BCRPBTA122 Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer, Clinical Research Extension Award Apply for HT942525BCRPCREA2 Funding Number: HT942525BCRPCREA2 Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Oyster Larval Transport/Hydrodynamic Modeling for the Herring Bay Sanctuary, Maryland Apply for W81EWF 25 SOI 0008 Funding Number: W81EWF 25 SOI 0008 Agency: Engineer Research and Development Center Category: Science and Technology and other Research and Development Funding Amount: $115,000 |
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| Monitoring Changes in Population Densities and Reproductive Success in Wading Bird Populations in the Florida Everglades for USACE Jacksonville District Apply for W9126G252SOI5006 Funding Number: W9126G252SOI5006 Agency: Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $825,000 |
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